by sdashiell Depression in Kids: Reading the Signs Most clinicians rely on the Diagnostic Statistical Manual of Mental Disorders (DSM) to diagnose their patients, which then informs their treatment plan. According the DSM, clinical depression is defined as depressed mood and loss of interest in … Read more on The Safety Report An Overview of Depression 1- Medication. There are several medications that are used to treat depression and, if you choose to take a medication or the doctor determines that medication may benefit you, they will likely try one of several ...