by Abode of Chaos Is Bipolar Disorder Like a Truth Serum? Could bipolar disorder "make" someone say or do bad things? In some people, yes, but that doesn't mean it's a truth serum. Bipolar episodes color a person's world and can affect and change reactions dramatically. Irritability, hostility and even rage … Read more on About – News & Issues Bipolar Disorder With Melancholic Features It is an extremely severe state of depression, with specific symptoms. Psychiatrists may expand a diagnosis of a bipolar depressive episode by saying "with melancholic features." Continuing my exploration of bipolar disorder in the DSM-5, ...